Table 4.
Event Rates and Association of PPM With 3-Year Endpoints
| Event Rate, % | Crude HR (95% CI) | P Value | Adjusted HR (95% CI) | P Value | |
|---|---|---|---|---|---|
| All-cause mortalitya | |||||
| Model 1 | |||||
| Severe PPM vs not severe PPM | 33.2 vs 21.6 | 1.65 (1.10-2.48) | 0.015 | 1.79 (1.16-2.78) | 0.009 |
| Model 2 | |||||
| Severe PPM vs non-PPM | 33.2 vs 21.7 | 1.65 (1.10-2.47) | 0.016 | 1.81 (1.16-2.81) | 0.008 |
| Moderate PPM vs non-PPM | 20.5 vs 21.7 | 0.95 (0.78-1.15) | 0.578 | 1.16 (0.90-1.38) | 0.310 |
| Cardiovascular mortalityb | |||||
| Model 1 | |||||
| Severe PPM vs not severe PPM | 16.8 vs 7.1 | 2.46 (1.35-4.48) | 0.003 | 2.70 (1.42-5.14) | 0.002 |
| Model 2 | |||||
| Severe PPM vs non-PPM | 16.8 vs 7.0 | 2.51 (1.37-4.57) | 0.003 | 2.74 (1.43-5.22) | 0.002 |
| Moderate PPM vs non-PPM | 7.8 vs 7.0 | 1.17 (0.85-1.60) | 0.332 | 1.14 (0.79-1.64) | 0.493 |
| Heart failure hospitalizationc | |||||
| Model 1 | |||||
| Severe PPM vs not severe PPM | 19.1 vs 11.4 | 1.88 (1.10-3.19) | 0.020 | 1.88 (1.07-3.28) | 0.027 |
| Model 2 | |||||
| Severe PPM vs non-PPM | 19.1 vs 11.4 | 1.90 (1.12-3.24) | <0.001 | 1.83 (1.04-3.20) | 0.035 |
| Moderate PPM vs non-PPM | 11.9 vs 11.4 | 1.11 (0.87-1.42) | 0.401 | 0.97 (0.73-1.26) | 0.840 |
CKD was defined as estimated glomerular filtration rate <60 mL/min/1.73 m2.
Abbreviations as in Table 1.
Adjusted for the following variables: age; sex; BSA; body mass index (BMI); Clinical Frailty Scale; NYHA functional class Ⅲ/Ⅳ; STS risk score; dyslipidemia; diabetes; atrial fibrillation; CAD; PAD; CKD; liver disease; COPD; previous pacemaker; mean aortic gradient; LVEF; stroke volume (SV) index; MR ≥moderate; TR ≥moderate; SPAP; and transfemoral approach.
Adjusted for the following variables: age; sex; BSA; BMI; Clinical Frailty Scale; NYHA functional class Ⅲ/Ⅳ; STS risk score; hypertension; dyslipidemia; atrial fibrillation; previous CABG; PAD; CKD; liver disease; COPD; previous pacemaker; mean aortic gradient; LVEF; SV index; MR ≥ moderate; TR ≥ moderate; and SPAP.
Adjusted for the following variables: age; sex; BSA; BMI; Clinical Frailty Scale; NYHA functional class Ⅲ/Ⅳ; STS risk score; hypertension; dyslipidemia; diabetes; atrial fibrillation; CAD; previous CABG; PAD; CKD; COPD; previous pacemaker; AVA; mean aortic gradient; LVEF; SV index; MR ≥moderate; TR ≥moderate; SPAP; and transfemoral approach.