Table 1.

Reports and studies of imiquimod use for oral neoplasm.

Study/Case report (Reference number)	Type of lesion	Dose schedule	Complete response	Duration of response
Case report (14)	PVL	3x per week for 6 weeks	100%	6 months
Study (15)	Oral precancer including PVL	5x per week for 6 weeks	31.6%	6 months in 75% of patients
Study (16)	Oral precancer	3x per week for 6 weeks	6.66% with +2-unit change	6 months
Case report (17)	Oral precancer	Daily for 6 weeks	100%	18 months
Case report (18)	Recurrent oral cancer	Daily for 2 weeks, tapered to once weekly after 2 months	100%	Continued once weekly for 4 years without recurrence
Case report (19)	Florid oral papillomatosis	Four cycles of 3x per week and 2 weeks pause	0%	Not available
Case report (20)	Florid oral papillomatosis	Every other day for 16 weeks	100%	2 years