Table 1.
Patient’s characteristics.
| All patients (n = 68) | SE (−) (n = 52) | SE (+) (n = 16) | p values | |
|---|---|---|---|---|
| Age | 75 (70, 75) | 74 (70, 77) | 75 (70, 80) | 0.36 |
| Body Mass Index, kg/m2 | 21.8 (19.1, 24.0) | 21.9 (19.5, 24.0) | 21.3 (18.8, 24.2) | 0.57 |
| Sex, male | 58 (85.3) | 43 (82.7) | 15 (93.8) | 0.43 |
| Smoking, ex/ current | 54 (79.4)/14 (20.6) | 44 (84.6)/ 8(15.4) | 10 (62.5)/ 6(37.5) | 0.078 |
| Pack-years | 51.5 (36, 73.5) | 52.5 (37.5, 73.5) | 46.5 (24.6, 83.3) | 0.66 |
| GOLD classification, A/ B/ C/ D |
19 (27.9)/ 23 (33.8)/ 6 (8.8)/ 20 (29.4) |
14 (27)/17 (33)/ 6 (12)/15 (29) |
5 (31)/6 (38)/ 0 (0)/5 (31) |
0.33 |
| COPD stage 1/2/3/4 |
14 (20.6)/38 (55.9)/ 12 (17.6)/4 (5.9) |
12 (23)/29 (56)/ 8 (15)/3 (6) |
2 (13)/9 (56)/ 4 (25)/1 (6) |
0.72 |
| Sputum, + | 36 (52.9) | 26 (50.0) | 10 (62.5) | 0.41 |
| SA colonization, +* | 7 (10.3) | 3 (11.5) | 4 (40.0) | 0.076 |
| LAMA, + | 48 (70.6) | 35 (67.3) | 13 (81.3) | 0.36 |
| LABA, + | 57 (83.8) | 42 (80.8) | 15 (93.8) | 0.44 |
| ICS, + | 21 (30.9) | 14 (26.9) | 7 (43.8) | 0.23 |
| Home oxygen use, + | 9 (13.2) | 6 (11.5) | 3 (18.8) | 0.43 |
| Antidepressant drugs, + | 3 (4.4) | 2 (3.9) | 1 (6.3) | 0.56 |
| ACE inhibitors, + | 1 (1.5) | 1 (1.9) | 0 (0) | > 0.99 |
| Pneumococcal vaccination, + | 34 (50) | 27 (51.9) | 7 (43.8) | 0.78 |
| Asthma, + | 10 (14.7) | 10 (19.2) | 0 (0) | 0.10 |
| Cerebrovascular disease, + | 7 (10.3) | 4 (7.7) | 3 (18.8) | 0.34 |
| Pneumonia < 2 year, + | 20 (29.4) | 16 (30.8) | 4 (25.0) | 0.76 |
| A history of pneumonia ≥ 2, + | 5 (7.4) | 3 (5.8) | 2 (12.5) | 0.58 |
| AE < 2 year, + | 19 (27.9) | 15 (28.8) | 4 (25.0) | > 0.99 |
| A history of AE ≥ 2, + | 8 (11.8) | 7 (13.5) | 1 (6.3 | 0.67 |
| Hospitalization < 2 year, + | 27 (39.7) | 21 (40.4) | 6 (37.5) | > 0.99 |
| A history of hospitalization ≥ 2, + | 10 (14.7) | 7 (13.5) | 3 (18.8) | 0.69 |
| mMRC scale, Grade | 1 (1, 3) | 1 (1, 3) | 1.5 (1, 3) | 0.52 |
| mMRC ≥ Grade 2, + | 33 (48.5) | 25 (48.1) | 8 (50) | > 0.99 |
| CAT, point | 13 (6, 18) | 14 (6, 19) | 12 (6, 18) | 0.88 |
| CAT ≥ 10, + | 39 (57.4) | 22 (42.3) | 7 (43.8) | > 0.99 |
| LCQ, point | 19.1 (17.3, 20.2) | 19.1 (16.9, 20.2) | 19.3 (17.4, 20.3) | 0.67 |
*n = 36 (SE [−]: n = 26/ SE [+]: n = 10)