Table 2. Multivariable Analysis for 30-Day Mortality in Patients with Persistent MRSA Bacteremia.
| Variable | Univariable | Multivariable | ||
|---|---|---|---|---|
| HR (95% CI) | p value | Adjusted HR (95% CI) | p value | |
| Sex, male | 0.57 (0.30–1.07) | 0.080 | 0.58 (0.29–1.16) | 0.124 |
| Age, per 1-year | 1.02 (0.99–1.05) | 0.113 | 1.02 (0.99–1.04) | 0.268 |
| Beta-lactams co-administration | 2.80 (1.33–5.89) | 0.007 | 1.07 (0.44–2.67) | 0.859 |
| Switching to other anti-MRSA agents | 0.39 (0.19–0.83) | 0.014 | 0.24 (0.03–2.17) | 0.238 |
| ICU admission within 24 hours* | 2.40 (1.27–4.51) | 0.007 | 1.81 (0.74–4.41) | 0.195 |
| Pitt bacteremia score, initial, per 1-point | 1.22 (1.07–1.40) | 0.003 | 0.86 (0.69–1.08) | 0.187 |
| Pitt bacteremia score, day 4, per 1-point* | 1.32 (1.19–1.47) | <0.001 | 1.31 (1.13–1.51) | <0.001 |
| Pneumonia | 4.83 (2.21–10.60) | <0.001 | 4.62 (1.72–12.42) | 0.002 |
| Echocardiography | 0.38 (0.20–0.70) | 0.002 | 0.53 (0.25–1.14) | 0.104 |
| Bacteremia duration, days, per 1-day | 0.94 (0.89–1.00) | 0.034 | 0.98 (0.92–1.04) | 0.477 |
MRSA, methicillin-resistant Staphylococcus aureus; HR, hazard ratio; CI, confidence interval; ICU, intensive care unit.
*Time points were calculated from the onset of bacteremia.