图6.

阻断NF-κB信号通路, SPHK1对GC细胞的迁移与侵袭能力的影响

Fig.6 Effect of blocking the NF-κB signaling pathway on migration and invasion ability of GC cells with SPHK1 knockdown or overexpression. A, B: Transwell assay for assessing migration and invasion of GC cells treated with 100 nmol/L PDTC (a NF-κB pathway inhibitor) or DMSO for 24 h (×200). C-F: Western blotting for detecting the levels of P65, p-P65, VEGFA and IL-17 proteins.*P<0.05, **P<0.01, ***P<0.001.