Table 3.

Calibration results per yearly time interval.

		Time (years)	Cox									RSF
			ICI			E50			E90			ICI			E50			E90
			LB	Mean	UB	LB	Mean	UB	LB	Mean	UB	LB	Mean	UB	LB	Mean	UB	LB	Mean	UB
Non-NST	LRR	1	0.0001	0.0002	0.0004	0.0000	0.0001	0.0004	0.0001	0.0003	0.0009	0.0002	0.0003	0.0005	0.0001	0.0002	0.0004	0.0002	0.0004	0.0009
		2	0.0002	0.0003	0.0008	0.0000	0.0002	0.0007	0.0003	0.0004	0.0016	0.0015	0.0020	0.0023	0.0006	0.0014	0.0016	0.0014	0.0018	0.0028
		3	0.0003	0.0005	0.0009	0.0002	0.0003	0.0008	0.0003	0.0008	0.0016	0.0033	0.0040	0.0043	0.0020	0.0028	0.0031	0.0033	0.0043	0.0051
		4	0.0003	0.0008	0.0012	0.0002	0.0004	0.0011	0.0004	0.0010	0.0023	0.0053	0.0059	0.0064	0.0035	0.0044	0.0049	0.0054	0.0069	0.0083
		5	0.0004	0.0008	0.0015	0.0002	0.0005	0.0014	0.0006	0.0011	0.0028	0.0072	0.0080	0.0086	0.0048	0.0058	0.0066	0.0075	0.0092	0.0107
	CBC	1	0.0001	0.0002	0.0005	0.0001	0.0001	0.0004	0.0002	0.0003	0.0009	0.0001	0.0003	0.0005	0.0001	0.0002	0.0006	0.0003	0.0005	0.0011
		2	0.0002	0.0004	0.0008	0.0002	0.0004	0.0008	0.0003	0.0007	0.0017	0.0006	0.0010	0.0014	0.0002	0.0008	0.0012	0.0008	0.0019	0.0032
		3	0.0003	0.0007	0.0013	0.0003	0.0006	0.0011	0.0006	0.0012	0.0026	0.0014	0.0025	0.0031	0.0013	0.0020	0.0027	0.0021	0.0048	0.0066
		4	0.0003	0.0009	0.0017	0.0002	0.0008	0.0016	0.0006	0.0015	0.0032	0.0032	0.0043	0.0049	0.0027	0.0038	0.0043	0.0049	0.0083	0.0104
		5	0.0004	0.0011	0.0021	0.0003	0.0010	0.0020	0.0007	0.0019	0.0039	0.0043	0.0056	0.0064	0.0038	0.0048	0.0056	0.0069	0.0109	0.0145
NST	LRR	1	0.0010	0.0015	0.0024	0.0007	0.0013	0.0019	0.0015	0.0024	0.0057	0.0007	0.0014	0.0026	0.0004	0.0010	0.0022	0.0011	0.0021	0.0047
		2	0.0017	0.0025	0.0038	0.0011	0.0021	0.0030	0.0029	0.0039	0.0088	0.0014	0.0035	0.0052	0.0005	0.0021	0.0039	0.0015	0.0038	0.0086
		3	0.0022	0.0031	0.0049	0.0014	0.0027	0.0040	0.0035	0.0051	0.0109	0.0029	0.0060	0.0083	0.0012	0.0038	0.0063	0.0033	0.0075	0.0157
		4	0.0026	0.0037	0.0054	0.0017	0.0033	0.0048	0.0039	0.0060	0.0117	0.0051	0.0085	0.0116	0.0026	0.0056	0.0088	0.0061	0.0116	0.0203
		5	0.0028	0.0040	0.0062	0.0019	0.0035	0.0052	0.0042	0.0065	0.0126	0.0069	0.0106	0.0140	0.0035	0.0069	0.0109	0.0085	0.0152	0.0233
	CBC	1	0.0004	0.0007	0.0018	0.0002	0.0005	0.0020	0.0007	0.0013	0.0026	0.0004	0.0006	0.0017	0.0003	0.0005	0.0015	0.0006	0.0013	0.0027
		2	0.0006	0.0012	0.0020	0.0004	0.0010	0.0021	0.0011	0.0020	0.0045	0.0004	0.0012	0.0019	0.0002	0.0009	0.0019	0.0006	0.0016	0.0036
		3	0.0007	0.0015	0.0027	0.0006	0.0013	0.0025	0.0012	0.0027	0.0055	0.0013	0.0020	0.0032	0.0005	0.0014	0.0024	0.0015	0.0021	0.0056
		4	0.0010	0.0020	0.0035	0.0007	0.0018	0.0034	0.0019	0.0039	0.0071	0.0025	0.0039	0.0054	0.0009	0.0027	0.0043	0.0028	0.0044	0.0082
		5	0.0012	0.0025	0.0043	0.0011	0.0022	0.0040	0.0021	0.0045	0.0086	0.0030	0.0047	0.0063	0.0015	0.0036	0.0053	0.0038	0.0054	0.0090

Values presented are for optimism adjusted values. Mean values are depicted in bold. Abbreviations: Cox = multivariable Cox model with restricted cubic splines. RSF = random survival forest model. NST = neoadjuvant systemic treatment. LRR = locoregional recurrence. CBC = contralateral breast cancer. ICI = integrated calibration index. E50 = the median absolute difference between observed and expected predictions. E90 = the 90th percentile of the absolute difference between observed and expected predictions. LB = 95 % lower bound. UB = 95 % upper bound.