Table 4.
Immunomodulatory activities of mushroom compounds on DCs.
| Species | Compound | Immune effects | Reference |
|---|---|---|---|
| G lucidum | Gl-PS | ↑ proliferation of one-way MLC induced by DC | [91] |
| P linteus | PL | ↑ phenotypic and functional maturation of DC | [92] |
| ↑ membrane molecules, including MHC I, II, CD80, and CD86, and IL-12p70 in DC | |||
| ↓ endocytic activity of DC | |||
| ↑ capacity of DC to promote the proliferation of naïve allogenic T cells and | |||
| readies them for T-cell-mediated immune responses | |||
| C versicolor | PSK | Promoted both the phenotypic and functional maturation of DC derived from | [95] |
| human CD14+ mononuclear cells | |||