Table 3.
Laboratory parameters of the participants and abdominal ultrasonic stages of steatosis in NAFLD patients
| Group I(n = 100) NAFLD patients |
Group II(n = 100) Healthy control |
P value | |
|---|---|---|---|
| Fasting blood Glucose(mg/dL) | 104.4 ± 8.3 | 96.5 ± 5.1 | 0.03 |
| ALT(IU/L) | 72.8 ± 11.6 | 12.7 ± 5.7 | < 0.001 |
| AST(IU/L) | 24.3 ± 7.3 | 20.4 ± 9.2 | 0.4 |
| Total cholesterol(mg/dl) | 186.2 ± 30.7 | 155.7 ± 17.5 | 0.01 |
| Triglycerides(mg/dL) | 92.2 ± 14.7 | 52.5 ± 11.6 | < 0.001 |
| HDL-cholesterol(mg/dL) | 56.3 ± 10.9 | 64.7 ± 11.2 | 0.01 |
| LDL-cholesterol(mg/dL) | 118.3 ± 19.4 | 91.1± 21.5 | < 0.001 |
| hs-CRP(mg/L) | 5.1 ± 1.1 | 0.6 ± 0.3 | < 0.001 |
| Uric acid(mg/L) | 4.9 ± 1.5 | 4.0 ± 0.9 | 0.04 |
| Iron(µg/dL) | 97.2 ± 29.5 | 102.6 ± 36.8 | 0.6 |
| TIBC(µg/dL) | 338.3 ± 40.5 | 327.8 ± 32.7 | 0.8 |
| Transferrin saturation (%) | 27.5± 7.3 | 30.9 ± 11.3 | 0.74 |
| Ferritin(ng/mL | 41.2 ± 18.4 | 35.2 ± 16.9 | 0.55 |
| 25-OH vitamin D(ng/mL | 11.2 ± 4.0 | 16.3 ± 7.2 | 0.03 |
| Insulin(µU/mL) | 12.8 ± 3.7 | 4.7 ± 2.5 | < 0.001 |
| HOMA-IR | 3.6 ± 1.1 | 1.3 ± 0.8 | < 0.001 |
| Hemoglobin(g/dL) | 13.8 ± 1.3 | 14.1 ± 1.1 | 0.4 |
| HbA1c (%) | 5.4 ± 0.8 | 5.2 ± 0.5 | 0.35 |
| Platelet count(×103/µL) | 255.8 ± 48.3 | 245.7 ± 50.3 | 0.9 |
| MPV(fL) | 7.2 ± 0.6 | 7.1 ± 0.8 | 0.77 |
| PDW (%) | 46.6 ± 2.8 | 44.9 ± 1.3 | 0.53 |
| WBC count(×103/µL) | 7.4 ± 1.4 | 5.9 ± 1.1 | 0.04 |
| Neutrophil count | 3.8 ± 2.1 | 2.6 ± 1.7 | 0.02 |
| Neutrophil % | 51.2 ± 7.5 | 42.8 ± 2.6 | 0.02 |
| Lymphocyte count(×103/µL) | 2.9 ± 0.8 | 2.6 ± 1.2 | 0.6 |
| Lymphocyte % | 37.8 6.2 | 44.2 7.0 | 0.1 |
| Monocyte count(×103/µL) | 0.4 ± 0.1 | 0.3 ± 0.1 | 0.8 |
| Eosinophil count(×103/µL) | 0.2 ± 0.1 | 0.2 ± 0.1 | 0.9 |
| Basophil count(×103/µL) | 0.1 | 0.1 | 0.82 |
| Neutrophil/lymphocyte ratio | 1.3 ± 0.4 | 0.9 ± 0.2 | 0.01 |
| TNF-α(pg/ml) | 22.6 ± 5.8 | 16.5 ± 3.6 | 0.003 |
| IL-17(pg/ml) | 14.7 ± 5.8 | 8.65± 3.08 | 0.01 |
| IL-10(pg/ml) | 9.4 ± 3.6 | 7.8 ± 1.5 | 0.04 |
| IL-12(pg/ml) | 74.1 ± 26.8 | 55.4 ± 22.6 | 0.01 |
| IL-23(pg/ml) | 61.4 ± 19.7 | 43.7 ± 18.6 | < 0.001 |
The data are expressed as the means ± standard deviations, and significant p values (< 0.05) are shown in bold
ALT: alanine aminotransferase; AST: aspartate aminotransferase; HDL: high-density lipoprotein; LDL: low-density lipoprotein; hs-CRP: high-sensitivity C-reactive protein; TIBC: total iron binding capacity; HbA1c: glycated hemoglobin; HOMA-IR: homeostasis model assessment of insulin resistance; MPV: mean platelet volume; PDW: platelet distribution width; WBC: white blood cell; TNF: tumor necrosis factor; IL: interleukin