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. 2024 Nov 25;17:9651–9664. doi: 10.2147/JIR.S490655

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© 2024 Qin et al.

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IRF2 influenced cell viability and migration in LPS+IFN-γ induced macrophages. Relative cell viability of different group (A) and representative images of transwell assay in each group (B) when IRF2 overexpression and silencing. Relative migration rate in different groups (RAW264.7 cells) (C); Mean±standard error of the mean values is presented for each group. *: LPS+IFN-γ group compared with control group, P < 0.05; #: LPS+IFN-γ+IRF2-pcDNA3.1 group compared with LPS+IFN-γ group and LPS+IFN-γ+pcDNA3.1 group, P < 0.05; @: LPS+IFN-γ+si-IRF2 group compared with LPS+IFN-γ group and LPS+IFN-γ+si-NC group, P < 0.05. P < 0.05 by one-way analyse of variance (ANOVA). Control group was defined as RAW264.7 cells without LPS+IFN-γ treated group. Scale bar, 100 μm.