FIG. 5.

Sequence similarities among Lbc, trychohyalin, and caldesmon. The sequences of the two proteins with the highest degrees of similarity with that of the proto-Lbc C terminus, as detected by BLAST, were aligned by using the Pileup multiple alignment program in the Genetics Computer Group package, and a consensus sequence was generated by using the Pretty program in extended GCG. The proto-Lbc residues shown (HPROTOLBC) are residues 651 to 764. HTRYCHOH, human trychohyalin residues 296 to 401; HCALDESM, human caldesmon residues 284 to 396.