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. Author manuscript; available in PMC: 2024 Nov 29.
Published in final edited form as: J Antimicrob Chemother. 2015 Jul 3;70(10):2763–2769. doi: 10.1093/jac/dkv186

Table 1.

List of resistance genes and their prevalence

Resistance gene Antibiotic class Resistance phenotype Prevalence (%)

strA [aph(3’)-Ib] aminoglycosides STR 75.0
strB [aph(6’)-Id] aminoglycosides STR 75.0
aadAl aminoglycosides STR 9.2
aadA2 aminoglycosides STR 9.2
aadA5 aminoglycosides STR 2.6
aadA7 aminoglycosides STR 1.3
aadA24 aminoglycosides STR 1.3
aph(3’)-Ia aminoglycosides KAN 14.5
aac(3’)-VI aminoglycosides GEN 2.6
aac(3’)-IId aminoglycosides GEN 1.3
bla TEM-1 β-lactams AMP 43.4
bla OXA-1 β-lactams AMP 1.3
bla CMY-2 β-lactams AMC, AMP, CRO, FOX, TIO 30.3
ampC (−42 T→C) β-lactams AMC, AMP, FOX 5.3
sul1 folate synthesis inhibitors FIS 17.1
sul2 folate synthesis inhibitors FIS 78.9
sul3 folate synthesis inhibitors FIS 2.6
dfrA1 folate synthesis inhibitors SXT 5.3
dfrA5 folate synthesis inhibitors SXT 1.3
dfrA12 folate synthesis inhibitors SXT 9.2
dfrA17 folate synthesis inhibitors SXT 2.6
mphA macrolides AZM 1.3
floR phenicols CHL 68.4
cmlA phenicols CHL 2.6
catA1 phenicols CHL 3.9
catB3 phenicols CHL 1.3
qnrB2 a quinolones NAL, CIP 1.3
qnrB6 a quinolones NAL, CIP 1.3
qnrS2 a quinolones NAL, CIP 1.3
gyrA mutations quinolones NAL, CIP 27.6
parC mutations quinolones NAL, CIP 10.5
parE mutations quinolones NAL, CIP 3.9
tet(A) tetracyclines TET 71.1
tet(B) tetracyclines TET 22.4
tet(C) tetracyclines TET 21.1
tet(D) tetracyclines TET 19.7
tet(M) tetracyclines TET 9.2

STR, streptomycin; KAN, kanamycin; GEN, gentamicin; AMP, ampicillin; AMC, amoxicillin/clavulanic acid; CRO, ceftriaxone; FOX, cefoxitin; TIO, ceftiofur; FIS, sulfisoxazole; SXT, trimethoprim/sulfamethoxazole; AZM, azithromycin; CHL, chloramphenicol; NAL, nalidixic acid; CIP, ciprofloxacin; TET, tetracycline.

a

Only confers reduced susceptibility.