FIG. 4.

The PI 3-kinase inhibitors and the DEX induction of Ras(N17) but not rapamycin abolish DNA synthesis (lower) and the induction of cyclin A protein (upper) in response to EGF. The inhibitors and DEX were introduced to the cells as described in the legend to Fig. 3, and the cells were incubated with EGF for 18 h. Abbreviations are as defined in the legend to Fig. 2.