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Activation of caspases is blocked in Bcl-2:HL-60 cells. HL-60 and Bcl-2:HL-60 cells were left untreated (−) or treated with 5 μM STS for 4 h (+). S-100 extracts were then prepared from the cells, and samples (100 μg) were subjected to Western blot analyses for the indicated caspases.