FIGURE 7.

Effects of H80 on glycemia during a mixed meal test in normoglycemic and prediabetic human participants. Sixteen healthy participants were orally administered 30 min before a carbohydrate‐rich, mixed meal: Placebo, H80 at 5 g or 10 g. Panels (A, D, G) show results of the total population (n = 16), panels (B, E, H) of the normoglycemic subgroup (n = 7), panels (C, F, I) of the prediabetic subgroup (n = 9). (A, B, C) Summary concentration‐time curves of blood glucose over time with treatment administration at T‐30, and mixed meal intake at 0 min. (D, E, F) Incremental AUC for glucose in response to the mixed meal. (G, H, I) Maximum glucose concentration corrected for baseline. All values are means ± 95% CI. Statistical significance was evaluated by linear mixed model with multiple paired comparisons of least squares means against placebo for iAUC. Δp < 0.1, *p < 0.05, **p < 0.01, ***p < 0.001.