Fig. 1.

High level expression of circVAPA in ARDS patients is associated with inflammation and oxidative stress

ELISA analysis of inflammatory factors (TNF-α, IL-1β and IL-6) in the BALF samples of ARDS patients and healthy controls (n = 10 in each group). (B) Myeloperoxidase (MPO) activity and (C) ROS level measurement in the BALF samples of ARDS patients and healthy controls. (D) Flow cytometry analysis of the expression of M1 marker (CD86) and M2 marker (CD206) in macrophages from BALF samples. (E) qRT-PCR detection of circVAPA expression in the macrophage samples from ARDS patients and healthy controls. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001