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. 2024 Nov 29;14:29720. doi: 10.1038/s41598-024-80986-y

Fig. 3.

Fig. 3

Comparison of ROC curve analysis for selected amino acids reveals significant differences in their ability to discriminate between the BPH group and the PCa group. Evaluation of diagnostic performance for individual amino acids as potential biomarkers in distinguishing prostate cancer from benign prostatic hyperplasia. A Glutamate (Glu) (AUC = 0.963, sensitivity = 82.9%, specificity = 96.7%). B Serine (Ser) (AUC = 0.800, sensitivity = 82.9%, specificity = 80.0%). C Histidine (His) (AUC = 0.813, sensitivity = 100%, specificity = 50.0%). D Arginine (Arg) (AUC = 0.750, sensitivity = 51.4%, specificity = 90.0%). E Aspartic acid (Asp) (AUC = 0.731, sensitivity = 74.3%, specificity = 73.3%). F Glycine (Gly) (AUC = 0.739, sensitivity = 65.7%, specificity = 83.3%).