The survival curve, calibration plot, and time-dependent ROC
curve of the nomogram in the training and validation cohorts. (A,B) Kaplan-Meier
survival for the incidence of CVD between males and females in the training and
validation cohorts. (C,D) Calibration plot of 3 and 5-year CVD risk prediction in
the training and validation cohorts. (E,F) Time-dependent ROC curves in the
training and validation cohorts. Abbreviations: CVD, cardiovascular disease; ROC,
receiver operator characteristic; AUC, area under the curve. Youden index =
sensitivity + specificity – 1.