Table 1.

Estimated model parameters

$a_{i,j}$	ADAS-cog	HippoV	CSF tau	AV45	$c_i$
ADAS-cog	0	−0.23286	0.04579	0.11301	−0.08587
HippoV	0	0	0	−0.06553	−0.42319
CSF tau	0	0	0	0.01371	0.10595
AV45	0	0	0	0	0.19057

This table summarizes the model parameters $a_{i,j}\in A$ and $c_i\in \overrightarrow{c}$ estimated by linear mixed effects models. The elements of A quantify how much the biomarkers in the rows of the table change depending on the biomarkers in the columns. The elements of $\overrightarrow{c}$ in the last column quantify how much the biomarkers in the rows of the table change depending on time. ADAS-cog, cognitive Alzheimer’s disease assessment scale; HippoV, hippocampal volume; CSF tau, corticospinal fluid total tau; AV45, florbetapir amyloid-PET score.