Figure 2.

This figure outlines key factors related to seizures induced by e-cigarettes. The etiology of symptoms remains unclear, with no consensus on a lethal dose of nicotine. High nicotine levels may cause neurological conditions, and symptoms can vary based on nicotine’s isomer and genetic differences in users. The timing of seizure presentation can be immediate due to nicotine’s high bioavailability or delayed due to its long half-life. The quality of evidence is impacted by the absence of other symptoms and the failure to account for co-morbidities in many case reports.