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Distribution of the results per isotype for the two-tier test strategies using Serion and Liaison as screening assay, stratified by study group. aNB: active Lyme neuroborreliosis, tNB: treated Lyme neuroborreliosis, aLA: active Lyme arthritis, tLA: treated Lyme arthritis, uHI: untreated healthy individuals, tHI: treated healthy individuals, CR: cross-reactivity controls, Ser: Serion, Lia: Liaison, C6: C6 Lyme ELISA, RL: recomLine, EU: Euroline
