Table 3.
Stratification analysis for associations between, PRNCR1 polymorphism and recurrent miscarriage risk in a south Chinese population.
| Variable | rs13252298 (cases/controls) | p-Value | Statistical power b | OR (95% CI) | p-Value | Adjust OR (95% CI) | p-value a | |
|---|---|---|---|---|---|---|---|---|
| AG + GG | AA | |||||||
| Age | ||||||||
| <35 | 122/133 | 310/207 | 0.0014 | 0.1148 | 0.613 (0.453–0.829) | 0.0015 | / | / |
| 35–40 | 65/44 | 96/61 | 0.8039 | 0.0152 | 0.939 (0.570–1.547) | 0.8037 | / | / |
| >40 | 32/17 | 12/9 | 0.5171 | 0.0774 | 1.412 (0.496–4.016) | 0.518 | / | / |
| No. of miscarriage/% | ||||||||
| 2–3 | 167/277 | 192/418 | 0.0379 | 0.0639 | 0.762 (0.589–0.985) | 0.0381 | 0.740 (0.571–0.959) | 0.0229 |
| 4⩾ | 27/277 | 27/418 | 0.1437 | 0.0534 | 0.663 (0.381–1.154) | 0.1437 | 0.656 (0.371–1.160) | 0.1471 |
a
Adjusted for age. Statistically significant values are shown in bold (p < 0.05).
b
Statistical power was calculated using the number of observations in each subgroup and the corresponding ORs and p-values in this table.