Table 4.
Cutoff according to Youden Index for significant inflammatory indices for endoscopic and histological activity
| Variable | Endoscopy activity | Histologic activity | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Cutoff | Sen (%) | 95% CI | Spe (%) | 95% CI | Cutoff | Sen (%) | 95% CI | Spe (%) | 95% CI | |
| CAR | >0.22 | 75.38 | 63.1–85.2 | 62.50 | 35.4–84.8 | |||||
| NLR | >2.32 | 51.03 | 42.6–59.4 | 75 | 57.8–87.9 | >1.94 | 63.87 | 54.6–72.5 | 65.79 | 48.6–80.4 |
| PLR | >147 | 42.76 | 34.6–51.2 | 80.56 | 64.0–91.8 | |||||
| SIRI | >1.29 | 45.52 | 37.2–54.0 | 77.78 | 60.8–89.9 | >0.75 | 80.67 | 72.4–87.3 | 39.47 | 24.0–56.6 |
CAR, C-reactive potein albumin ratio; CI: confidence interval; NLR, neutrophil-to-lymphocytes ratio; PLR, platelets-to-lymphocytes ratio; SEN, sensitivity; SIRI, systemic inflammation response index; SPE, specificity.