TABLE 3.
Quality-of-Life Analyses for Cycle A
| Outcome | Baseline | Day 6 (or 7, 8) | Mean Differencea | P | ||
|---|---|---|---|---|---|---|
| THC:CBD | Placebo | THC:CBD | Placebo | |||
| FLIE summary scalesb | ||||||
| Nausea domain | 63 | 62 | 67 | 48 | 19 | <.01 |
| Vomiting domain | 83 | 84 | 89 | 84 | 6 | .11 |
| AQOL-8D summary scalesc | ||||||
| Independent living | 0.77 | 0.78 | 0.70 | 0.71 | –0.00 | .91 |
| Happiness | 0.75 | 0.76 | 0.70 | 0.69 | 0.02 | .40 |
| Mental health | 0.63 | 0.62 | 0.64 | 0.62 | 0.01 | .60 |
| Coping | 0.74 | 0.73 | 0.66 | 0.67 | –0.01 | .59 |
| Relationships | 0.69 | 0.67 | 0.64 | 0.64 | –0.01 | .68 |
| Self-worth | 0.77 | 0.79 | 0.73 | 0.75 | –0.00 | .96 |
| Pain | 0.69 | 0.76 | 0.75 | 0.74 | 0.06 | .05 |
| Sensitivity | 0.85 | 0.86 | 0.86 | 0.85 | 0.01 | .44 |
| Super dimension mental | 0.36 | 0.35 | 0.30 | 0.31 | –0.01 | .76 |
| Super dimension physical | 0.61 | 0.66 | 0.60 | 0.60 | 0.03 | .24 |
| AQOL-8D utility | 0.66 | 0.67 | 0.62 | 0.61 | 0.01 | .68 |
Abbreviations: AQOL-8D, Assessment of Quality of Life—eight dimensions; CBD, cannabidiol; FLIE, Functional Living Index—Emesis; THC, tetrahydrocannabinol.
a
Adjusted for baseline, positive results favor THC:CBD.
b
Scale 0-100, higher score indicated better quality of life.
c
Scale 0-1, higher score indicates better quality of life.