Table 3.
Baseline characteristics of patients with or without statins.
| All patients (N = 12,200) | With statins (N = 11,415) | Without statins (N = 785) | P value | |
|---|---|---|---|---|
| Age (yr) | 63.6 ± 12.6 | 63.4 ± 12.5 | 66.6 ± 12.5 | <.001 |
| Male | 9067 (74.3) | 8533 (74.8) | 534 (68.0) | <.001 |
| Body mass index (kg/m2) | 24.05 ± 3.31 | 24.08 ± 3.31 | 23.54 ± 3.32 | <.001 |
| Hypertension | 6156 (50.5) | 5731 (50.2) | 425 (54.1) | .035 |
| Diabetes mellitus | 3411 (28.0) | 3108 (27.2) | 303 (38.6) | <.001 |
| Prior angina pectoris | 1159 (9.5) | 1060 (9.3) | 99 (12.6) | .003 |
| Prior myocardial infarction | 934 (7.7) | 848 (7.4) | 86 (11.0) | <.001 |
| Prior heart failure | 180 (1.5) | 147 (1.3) | 33 (4.2) | <.001 |
| Prior stroke | 795 (6.5) | 717 (6.3) | 78 (9.9) | <.001 |
| Current smoker | 4849 (39.7) | 4615 (40.4) | 234 (29.8) | <.001 |
| Killip class ≥ II | 2436 (20.0) | 2147 (18.8) | 289 (36.8) | <.001 |
| eGFR < 60 mL/min/1.73m2 | 2217 (18.2) | 1946 (17.0) | 271 (34.5) | <.001 |
| Left ventricular EF (%) | 52.2 ± 11.0 | 52.4 ± 10.8 | 49.3 ± 12.7 | <.001 |
| STEMI | 5806 (47.6) | 5498 (48.2) | 308 (39.2) | <.001 |
| Coronary reperfusion* | 11,661 (95.6) | 10.964 (96.0) | 697 (88.8) | <.001 |
| Medications at discharge | ||||
| Aspirin | 12,160 (99.7) | 11,389 (99.8) | 771 (98.2) | <.001 |
| P2Y12 inhibitor | 11,666 (95.6) | 11,014 (96.5) | 652 (83.1) | <.001 |
| Beta-blockers | 10,251 (84.0) | 9725 (85.2) | 526 (67.0) | <.001 |
| RAS inhibitors | 9729 (79.7) | 9232 (80.9) | 497 (63.3) | <.001 |
Values are mean ± standard deviation or number (%).
Abbreviations: EF = ejection fraction, eGFR = estimated glomerular filtration rate, RAS = renin-angiotensin system, STEMI = ST-elevation myocardial infarction.
*
Included reperfusion by percutaneous coronary intervention, thrombolysis, or coronary artery bypass graft, myocardial infarction with non-obstructed coronary arteries and myocardial bridge.