TABLE 2.

Histopathologic characteristics of the patient cohort

	Patient 1	Patient 2	Patient 3	Patient 4	Patient 5
Liver histology	Microvesicular steatosis, centro-lobular necrosis, portal fields, and bile ducts regular, no signs of cholestasis, no signs of inflammation	NA	Micronodular cirrhosis, canalicluar and hepatocellular cholestasis, lack of steatosis	Severe parenchymal damage, bridging collapse, and severe cholestasis. Steatosis maximal in regenerative nodules, few multinucleate giant cells	Low hepatic damage, low bilirubinostasis, low chronic cholestasis signs, signs of clearance reaction and regeneration, portal/septal fibrosis, signs of ER activation, lack of steatosis.

Abbreviations: ER, endoplasmic reticulum; NA, not available.