Table 1.
Baseline characteristics of different diabetic subjects.
| HVs(n=42) | DM(n=68) | DN(n=53) | F/H value | P value | |
|---|---|---|---|---|---|
| Female n(%) | 18 (42.8%) | 29 (42.6%) | 18 (34%) | 7.130 | 1.458 |
| Age (years, ± SD) |
46.381 ± 12.165 | 50.941 ± 12.456 | 55.566 ± 10.613 | 1.140 | 0.001 |
| BMI(kg/m2, ± SD ) | 23.671 ± 3.039 | 28.494 ± 3.622 | 26.852 ± 3.142 | 27.333 | <0.01 |
| SBP (mmHg, ± SD) | 108.5 ± 7.178 | 133.632 ± 11.398 | 134.679 ± 18.883 | 55.729 | <0.01 |
| DBP (mmHg, ± SD) | 74.167 ± 7.708 | 81.088 ± 8.954 | 81.981 ± 10.148 | 10.278 | <0.01 |
| ALT [U/L,M(Q1,Q3)] | 30.45(22.475,40.025) | 24.25(18.825,44.75) | 20.5(14.5,31.8) | 9.408 | 0.009 |
| AST [U/L,M(Q1,Q3)] | 27.25(21.175,34.75) | 21.65(16.925,28.8) | 21(15.85,27.9) | 9.542 | 0.008 |
| ALB(g/L) | 48.410 ± 4.478 | 44.201 ± 4.618 | 41.691 ± 5.087 | 23.717 | <0.01 |
| AG | 1.510 ± 0.157 | 1.645 ± 0.264 | 1.468 ± 0.247 | 9.379 | <0.01 |
| BUN [mmol/L,M(Q1,Q3)] | 5.65(4.675,7.05) | 5.08(4.26,6.263) | 6.87(5.55,9.29) | 27.350 | <0.01 |
| SCr [umol/L,M(Q1,Q3)] | 61.65(56.15,65.925) | 63.3(54.575,72.15) | 74.7(63.45,123.25) | 43.239 | <0.01 |
| UA [umol/L, M(Q1,Q3)] | 271.2(247.225,293.575) | 335.25(260.6,389.25) | 382.2(315.8,427.65) | 40.422 | 0.043 |
| eGFR [ml/min/1.73m2, M(Q1,Q3)] | 107.78(100.915,116.6775) | 105.978(99.4,112.99) | 84.51(50.635,102.33) | 43.239 | <0.01 |
| UMA [mg/24h,M(Q1,Q3)] | 9.75(3.1,14.45) | 11.88(6.7,29.2) | 110.1(56.015,1082.665) | 85.683 | <0.01 |
| Pro | 0(0,0) | 0(0,0) | 1(0,2) | 70.778 | <0.01 |
| ACR [mg/g, M(Q1,Q3)] | 6.9(5.5,8.725) | 9.333(6.275,13.374) | 223.21(43.505,223.21) | 92.915 | <0.01 |