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. 2024 Nov 18;11:1424576. doi: 10.3389/fcvm.2024.1424576

Table 2.

Baseline laboratory and echocardiographic characteristics of the patients according to the presence of anemia.

Total Anemia No anemia P
Laboratory indicators
RBC 4.0 ± 0.9 3.7 ± 1.1 4.4 ± 0.4 <0.0001
HCT 36.9 ± 7.3 33.2 ± 4.5 41.4 ± 7.5 <0.0001
MCV 93.4 ± 14.4 92.3 ± 11.8 94.7 ± 17.0 0.7693
MCH 30.2 ± 3.6 29.5 ± 4.4 31.0 ± 2.0 0.0002
MCHC 324.6 ± 25.5 319.9 ± 27.7 330.4 ± 21.0 <0.0001
FIB 3.4 ± 2.4 3.5 ± 1.7 3.4 ± 3.0 0.0090
CRP 8.4 ± 13.5 10.2 ± 15.1 6.0 ± 10.8 <0.0001
ALT 22.7 ± 15.7 21.7 ± 14.8 24.0 ± 16.7 0.0296
AST 25.9 ± 16.1 25.8 ± 13.9 26.0 ± 18.5 0.5468
Cr 84.7 ± 40.2 91.9 ± 43.8 75.8 ± 33.3 <0.0001
TG 1.6 ± 1.0 1.5 ± 1.0 1.8 ± 1.1 0.0001
TC 4.2 ± 1.3 3.9 ± 1.1 4.5 ± 1.4 <0.0001
HDL 1.2 ± 0.5 1.2 ± 0.4 1.3 ± 0.5 0.0016
LDL 2.2 ± 0.9 2.0 ± 0.8 2.4 ± 0.9 0.0001
NT-pro-BNP 3467.4 ± 3535.5 4218.9 ± 3685.2 2533.5 ± 3105.7 <0.0001
TR, n (%) <0.0001
 Mild 250 (64.4) 105 (48.8) 145 (83.8)
 Moderate 61 (15.7) 48 (22.3) 13 (7.5)
 Severe 77 (19.9) 62 (28.9) 15 (8.7)
Echocardiography
LAD, mm 38.3 ± 8.0 39.6 ± 8.4 36.7 ± 7.1 0.0006
LVEF% 62.0 ± 7.9 61.8 ± 7.9 62.2 ± 7.9 0.6377
E/e' 15.5 ± 2.4 16.1 ± 2.6 14.8 ± 1.8 <0.0001
TAPSE, mm 18.7 ± 5.2 19.0 ± 18.0 19.2 ± 5.0 0.0111
PASP, mmHg 33.9 ± 15.0 41.0 ± 36.0 27.2 ± 12.1 <0.0001
TAPSE/PASP, mm/mmHg 0.68 ± 0.40 0.54 ± 0.28 0.85 ± 0.46 <0.0001

Bold values indicate P < 0.05.

Values are means ± SD.

RBC, red blood count; HCT, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; FIB, fibrinogen; CRP, C-reactive protein; ALT, alanine aminotransferase; AST, aspartate aminotransferase; Cr, creatinine; TG, triglyceride; TC, total cholesterol; HDL, high density lipoprotein; LDL, low density lipoprotein; NT-pro-BNP, NH2-terminal pro-brain-type natriuretic peptide; TR, tricuspid regurgitation; LAD, left atrial diameter; LVEF, left ventricular ejection fraction; E/e', early diastolic mitral inflow velocity/early diastolic mitral annulus velocity; TAPSE, tricuspid annular plane systolic excursion; PASP, pulmonary arterial systolic pressure.