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. 2024 Dec 2;14:29851. doi: 10.1038/s41598-024-76322-z

Table 1.

Baseline characteristics of I-ELCAP participants in New York State who died of GI cancer. Notably, there were significantly more men than women. The mean pack-years was high (> 50 pack-years), and the mean age at death was 75.9 years.

All GI cancers
(n = 189) (%)
Pancreas
n = 79 (%)
Esophagus
n = 33 (%)
Colon
n = 32 (%)
Liver
n = 18 (%)
Gastric
n = 16 (%)
Bile duct carcinoma
n = 6 (%)
Rectum n = 4 (%) Gallbladder
n = 1 (%)
P-value

Age at baseline

Mean (standard deviation)

67.1 (6.20) 66.9 (6.74) 67.3 (4.83)

66.6

(5.10)

66.9

(7.43)

69.2

(7.17)

67.0

(7.27)

64.5

(3.11)

72.0

(-)

0.83

Age at deaths

Mean (standard deviation)

75.9 (7.36) 75.0 (7.88) 76.2 (7.10) 75.8 (6.55) 75.4 (6.62) 79.6 (6.69) 78.7 (9.67) 74.0 (7.62) 78.0 (-) 0.41
Female 72 (38) 33 (41.3) 5 (15) 18 (56) 6 (33) 3 (19) 2 (33) 4 (100) 1 (100) < 0.05
Male 117 (62) 46 (57.5) 28 (85) 14 (44) 12 (67) 13 (81) 4 (67) 0 (0) 0 (0)

Race

African American/ West

Indian

16 (8.6) 5 (6.3) 3 (9.1) 4 (13) 3 (17) 1 (6.7) 0 (0) 0 (0) 0 (0) 0.56
Asian 3 (1.6) 1 (1.3) 1 (3) 0 (0) 1 (5.6) 0 (0) 0 (0) 0 (0) 0 (0)
Spanish/ Hispanic/ Latino 3 (1.6) 1 (1.3) 0 (0) 1 (3.2) 0 (0) 0 (0) 0 (0) 1 (25) 0 (0)
Caucasian 163 (88) 70 (87.5) 29 (88) 26 (84) 14 (78) 14 (93) 6 (100) 3 (75) 1 (100)
Patient reported comorbidity
Diabetes 12 (6.3) 8 (10) 1 (3) 1 (3.1) 2 (11) 0 (0) 0 (0) 0 (0) 0 (0) 0.64
Asthma 14 (7.4) 73 (91.3) 33 (100) 27 (84) 17 (94) 16 (100) 4 (67) 4 (100) 1 (100) 0.07
Emphysema or COPD 30 (16) 16 (20) 5 (15) 2 (6.2) 3 (17) 3 (19) 1 (17) 0 (0) 0 (0) 0.70
High Cholesterol 7 (3.7) 3 (3.8) 1 (3) 1 (3.1) 0 (0) 1 (6.2) 0 (0) 1 (25) 0 (0) 0.44
Hypertension 19 (10.1) 6 (7.5) 5 (15) 3 (9.4) 2 (11) 2 (12) 0 (0) 1 (25) 0 (0) 0.71
Peripheral Vascular Disease 1 (0.5) 0 (0) 0 (0) 1 (3.1) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0.41
Myocardial infarction 3 (1.6) 1 (1.3) 0 (0) 1 (3.1) 0 (0) 0 (0) 1 (17) 0 (0) 0 (0) 0.24
Stroke 6 (3.2) 3 (3.8) 1 (3) 2 (6.2) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0.90
Liver disease 1 (0.5) 0 (0) 0 (0) 1 (3.1) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0.41
Other cancer 5 (2.6) 2 (2.5) 2 (6.1) 0 (0) 0 (0) 1 (6.2) 0 (0) 0 (0) 0 (0) 0.59
Smokers/ Current 187 (99)/ 94 (52) 77 (97) / 36 (49) 33 (100)/ 14 (44) 32 (100)/ 18 (56) 18 (100)/ 12(67) 16 (100)/ 8(53) 6 (100)/ 3(50) 4 (100)/ 3 (75) 1 (100)/ 0(0)

Pack-years

Mean (standard deviation)

53.9 (28.5) 50.0 (24.7) 58.4 (29.0) 53.8 (30.2) 55.6 (22.2) 59.1 (35.0) 69.9 (57.6) 37.5 (22.2) 60.0 (-) 0.86
Family history of lung cancer 26 (14) 11 (14) 2 (6.1) 3 (9.4) 2 (11) 4 (25) 3 (50) 1 (25) 0 (0) 0.12