Table 2.
Laboratory measurements of parameters of the coagulation system. Results are corrected by the Benjamini–Hochberg procedure to control for false discovery rates.
| Parameter | Total n= 87 |
DIC n = 35 | No DIC n = 52 | P value |
|---|---|---|---|---|
| D-dimer (μg/L) | 4241 (2005-9003) | 7927 (4520-13,052) | 2339 (1406-4607) | <.001 |
| aPTT (s) | 43 (36-55) | 54 (45-59) | 37 (34-44) | <.001 |
| PT (%) | 67 (52-83) | 53 (38-61) | 74 (65-91) | <.001 |
| INR | 1.30 (1.10-1.50) | 1.45 (1.30-1.88) | 1.20 (1.10-1.30) | <.001 |
| Fibrinogen (mg/dL) | 570 (419-641) | 485 (363-610) | 574 (489-672) | .066 |
| Platelets (G/L) | 103 (51-188) | 48 (14-81) | 167 (103-258) | <.001 |
| Antithrombin (%) | 59 (49-71) | 52 (42-60) | 65 (53-76) | .004 |
| EV (nM) | 28.34 (14.12-50.14) | 29.62 (16.26-49.96) | 27.85 (11.78-48.82) | .63 |
| TF-PCA (TF eq pg/mL) | 0.47 (0.13-1.47) | 0.69 (0.25-1.60) | 0.28 (0.06-1.42) | .12 |
| TF (pg/mL) | 100 (73-131) | 104 (70-136) | 100 (75-123) | .69 |
| TFPI (ng/mL) | 28.74 (21.63-53.18) | 32.58 (25.47-67.48) | 25.40 (18.76-45.00) | .01 |
| E-selectin (ng/mL) | 163.2 (67.9-391.8) | 131.8 (49.3-414.7) | 177.8 (82.9-370.7) | .54 |
aPTT, activated partial thromboplastin time; DIC, disseminated intravascular coagulopathy; EV, extracellular vesicle; INR, international normalized ratio; PT, prothrombin time; TF, tissue factor; TF-PCA, tissue factor procoagulant activity; TFPI, tissue factor pathway inhibitor.