Table 1.
Characteristics of patients with PSVD or cirrhosis and HVs.
| PSVD (n = 20) | Cirrhosis (n = 20) | HVs (n = 20) | p value | |
|---|---|---|---|---|
| Age, years | 51.0 (36.3-55.0) | 53.0 (44.0-60.1) | 52.2 (39.7-58.9) | 0.414 |
| Male sex | 13 (65.0%) | 16 (80.0%) | 13 (65.0%) | 0.699 |
| BMI, kg/m2 | 25.6 (22.9-28.4) | 25.9 (25.0-27.7) | - | 0.791 |
| History of decompensation | 6 (30.0%) | 8 (40.0%) | - | 0.740 |
| LSM, kPa | 7.8 (5.9-8.8) | 30.2 (23.9-67.5) | - | <0.001 |
| HVPG, mmHg | 5 (4-8) | 18 (13-19) | - | <0.001 |
| Child-Pugh score, points | 6 (5-7) | 6 (5-6) | - | 0.522 |
| Child-Pugh stage A | 14 (70.0%) | 16 (80.0%) | - | 0.715 |
| Child-Pugh stage B/C | 6 (30.0%) | 4 (20.0%) | - | |
| MELD | 8 (7-10) | 8 (8-10) | - | 0.699 |
| Platelet count, G/L | 82 (63-117) | 84 (70-113) | - | 0.642 |
| Albumin, g/dl | 42.7 (39.8-44.5) | 39.5 (36.8-40.7) | - | 0.009 |
| Spleen length, cm | 16.0 (14.5-17.5) | 14.0 (12.0-15.0) | 0.040 | |
| Specific clinical signs of portal hypertension | 20 (100%) | 20 (100%) | - | - |
| Varices | 19 (95.0%) | 19 (95.0%) | - | 1.000 |
| Portosystemic collaterals | 18 (90.0%) | 15 (75.0%) | - | 0.405 |
| Unspecific clinical signs of portal hypertension | 19 (95.0%) | 19 (95.0%) | - | 1.000 |
| Ascites | 2 (10.0%) | 8 (40.0%) | - | 0.068 |
| Thrombocytopenia | 16 (80.0%) | 18 (90.0%) | - | 0.661 |
| Splenomegaly | 18 (90.0%) | 14 (70.0%) | - | 0.235 |
HV, healthy volunteers; HVPG, hepatic venous pressure gradient; LSM, liver stiffness measurement; PSVD, porto-sinusoidal vascular disorder; Student’s t test, Mann-Whitney U test, Pearson's Chi-squared test, Fisher’s exact test. Bold value represents p <0.05.