TABLE 2.
Preintervention imaging, interventional, and postinterventional outcome parameters compared between patients with and without prolonged venous transit.
| Variable | Overall, N = 104 | PVT– group | PVT+ group | p a |
|---|---|---|---|---|
| N = 74 | N = 30 | |||
| ASPECTS, median (IQR) | 9.00 (7.75, 10.00) | 9.00 (8.00, 10.00) | 10.00 (7.25, 10.00) | 0.67 |
| rCBF <20% volume, median (IQR), mL | 0 (0, 8) | 0 (0, 8) | 0 (0, 11) | 0.22 |
| Mismatch volume, median (IQR), mL | 93 (57, 133) | 81 (46, 118) | 118 (86, 170) | <0.001 |
| Mismatch ratio, median (IQR) | 3.9 (2.8, 7.4) | 3.9 (2.5, 7.2) | 4.4 (3.4, 7.9) | 0.6 |
| Hypoperfusion intensity ratio, median (IQR) | 0.40 (0.20, 0.50) | 0.35 (0.20, 0.50) | 0.45 (0.30, 0.50) | 0.18 |
| CBV index, median (IQR) | 0.80 (0.70, 0.90) | 0.80 (0.70, 0.90) | 0.80 (0.70, 0.90) | 0.8 |
| PVT, n (%) | 30 (29) | 0 (0) | 30 (100) | <0.001 |
| Tan score (0–3), median (IQR) | 2.00 (1.00, 2.00) | 2.00 (1.00, 2.00) | 2.00 (1.00, 2.00) | 0.089 |
| IVT administered, n (%) | 32 (31) | 24 (32) | 8 (27) | 0.56 |
| MT attempted, n (%) | 104 (100) | 74 (100) | 30 (100) | |
| Symptom onset to door time, median (IQR) min | 71 (42, 132) | 67 (44, 128) | 79 (38, 140) | >0.99 |
| Door to CT time (min), median (IQR), min | 31 (20, 57) | 32 (18, 52) | 28 (22, 52) | 0.82 |
| Door to needle time, median (IQR), min | 60 (46, 83) | 61 (44, 82) | 59 (53, 82) | 0.92 |
| Door to groin puncture time, median (IQR), min | 155 (127, 220) | 161 (129, 216) | 139 (124, 224) | 0.55 |
| Door to recanalization time, median (IQR), min | 277 (198, 355) | 257 (203, 364) | 294 (194, 325) | >0.99 |
| Groin puncture to recanalization time, median (IQR), min | 29 (23, 37) | 25 (19, 31) | 35 (30, 65) | 0.015 |
| mTICI score, n (%) | ||||
| 2b | 30 (29) | 21 (28) | 9 (30) | 0.16 |
| 2c | 20 (19) | 11 (15) | 9 (30) | |
| 3 | 54 (52) | 42 (57) | 12 (40) | |
| Hemorrhagic transformation, n (%) | 48 (46) | 33 (45) | 15 (50) | 0.62 |
| Type of hemorrhagic transformation, if present, n (%) | ||||
| HI1 | 9 (8.7) | 7 (9.5) | 2 (6.7) | 0.32 |
| HI2 | 17 (16) | 11 (15) | 6 (20) | |
| PH1 | 13 (13) | 11 (15) | 2 (6.7) | |
| PH2 | 9 (8.7) | 4 (5.4) | 5 (17) | |
| Discharge NIHSS score, median (IQR) | 4 (2, 9) | 3 (1, 6) | 9 (4, 12) | <0.001 |
| mRS score at 90 days, median (IQR) | 2.00 (1.00, 4.00) | 2.00 (1.00, 3.75) | 4.00 (2.25, 6.00) | <0.001 |
Abbreviations: ASPECTS, Alberta Stroke Program Early Computed Tomograpy Score; CBV, Cerebral Blood Volume; CT, computed tomography; IQR, interquartile range; IVT, intravenous thrombolysis; mRS, modified Rankin Scale; MT, mechanical thrombectomy; mTICI, modified Thrombolysis in Cerebral Infarction; NIHSS, National Institutes of Health Stroke Scale; PVT, prolonged venous transit; rCBF, relative cerebral blood flow.
a
Wilcoxon rank sum test; Pearson's Chi‐squared test; Fisher's exact test.