TABLE 5.
Evaluation of web‐based tools to predict prognosis in OTSCC.
| Web‐based tools | Positive (%) | Negative (%) | Total | Area under ROC curve (95% CI) | p‐value | Number and sensitivity (%) | Number and Specificity (%) | Accuracy (%) |
|---|---|---|---|---|---|---|---|---|
| Prediction of locoregional recurrence‐free survival | ||||||||
| (A) Recurrence‐free survival a | 57 (74.02) | 20 (25.98) | 77 | 0.691 (0.56–0.81) | 0.011 | 9 (45) | 45 (78.9) | 70 |
| (B) Recurrence‐free survival (Net benefit) | 96 (71.11) | 39 (28.89) | 135 | 0.574 (0.46–0.68) | 0.179 | 47 (49.0) | 25 (64.1) | 53 |
| (B) Recurrence‐free survival (Surgery alone) | 96 (71.11) | 39 (28.89) | 135 | 0.468 (0.36–0.57) | 0.440 | 57 (59.4) | 14 (35.9) | 52 |
| (B) Recurrence‐free survival (Surgery + RT) | 96 (71.11) | 39 (28.89) | 135 | 0.508 (0.40–0.61) | 0.949 | 52 (54.2) | 14 (35.9) | 48 |
| Prediction of risk of recurrence | ||||||||
| (E) Risk of locoregional recurrence b | ‐ | ‐ | 58 | ‐ | ‐ | 10 (52.6) | 8 (97.4) | 82 |
| Prediction of survival | ||||||||
| (B) 5‐year survival OS | 77 (57.03) | 58 (42.97) | 135 | 0.636 (0.54–0.72) | 0.007 | 42 (54.5) | 32 (55.2) | 54 |
| Prediction of cancer‐related mortality | ||||||||
| (C) Years mean survival DSS | 107 (79.25) | 28 (20.75) | 135 | 0.729 (0.62–0.83) | <0.001 | 88 (82.2) | 14 (50.0) | 75 |
| (C) 10‐year cancer mortality | 28 (20.75) | 107 (79.25) | 135 | 0.858 (0.78–0.93) | <0.001 | 23 (82.1) | 81 (75.7) | 77 |
| (C) Kaplan–Meier death rate | 28 (20.75) | 107 (79.25) | 135 | 0.765 (0.67–0.85) | <0.001 | 23 (82.1) | 77 (72.0) | 74 |
| (D) 5‐year survival rate DSS | 107 (79.25) | 28 (20.75) | 135 | 0.723 (0.62–0.82) | <0.001 | 84 (78.5) | 17 (60.7) | 74 |
Abbreviations: DSS, Disease‐specific survival; OS, Overall survival; RT, Radiotherapy.
a
77 cases were included as smoking status was unknown.
b
58 cases were included to exclude data used in our previous study/AUC curve was not feasible.