Baerveldt 2010.

Methods	This was a prospective, double‐blind, randomised, internally‐controlled trial.
Participants	Inclusion criteria of the trial Adults with fingernail psoriasis of both hands for at least 6 months A minimum of at least 2 affected nails on the left hand and the right hand, and the number of affected nails may have differed by 1 nail at the maximum on the left hand compared with those on the right hand The dose of oral medication before the start had to have been constant for 8 weeks, and it would be reasonably expected that the dose would not be altered during the treatment phase of the study. The trial evaluated 30 participants with a baseline NAPSI of 18.3 in the ciclosporin group and 16.9 at the placebo group (with a maximum score of 40).
Interventions	On the left and right fingernails either placebo or 100 mg/ml ciclosporin application, twice daily. The duration of the treatment was until complete cure or for a maximum of 16 weeks, with the control group treated for a maximum of 28 weeks. The follow up was for 12 weeks after stopping the treatment.
Outcomes	Outcomes of the trial Nail Psoriasis Severity Index (NAPSI)
Notes	6 participants dropped out because of non‐compliance, protocol violation, or the start of systemic therapy.