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. 2024 Dec 2;19(12):e0313091. doi: 10.1371/journal.pone.0313091

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© 2024 Penman et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 2 — Concentration of exogenous cannabinoids in whole brain samples following a 10 min inhalation dose of 5 mg/pad THC in FABP7^+/+ and FABP7^-/- mice, normalized to subject bodyweight. (A) Females had greater levels of THC in the brain compared to males, regardless of genotype. (B) FABP7^+/+ females had increased 11-OH-THC levels compared to FABP7^+/+ males. FABP7^-/- females had reduced 11-OH-THC levels compared to FABP7^+/+ females. #p<0.05 main sex effect, ##p<0.01 sex effect, **p<0.01 genotype effect.