Fig 8. Pioglitazone pre-treatment reduced the protein expression of NFκB p65 and increased the protein expression of Nrf2 in colistin-treated HK-2 cells compared to colistin-only treated cells.

The effect of pioglitazone 100 μM pre-treatment for 30 minutes on HK-2 cells treated with colistin 1200 μM for 24 hours on the protein expression of (a) NFκB p65 and (b) Nrf2. Data mean ± SEM (n = 3). ^#p < 0.05 vs. the control group, ^*p <0.05 vs. the colistin-treated group. Statistical analysis was performed with one-way ANOVA with Tukey’s multiple comparisons tests to compare the significance between treatment groups.