Table 4.
Models | Subtype* | Model Outputs |
Age | Stage** | Ancestry | nSES*** | |||||
---|---|---|---|---|---|---|---|---|---|---|---|
II | III | IV | African / European |
Native American / European |
East Asian / European |
2 | 3 | ||||
Age + Stage | ER+/HER2+ | OR | 0.998 | 2.519 | 3.522 | 2.036 | |||||
P | 0.873 | 0.041 | 0.013 | 0.539 | |||||||
95% CI | 0.968-1.027 | 1.04-6.104 | 1.3-9.535 | 0.211-19.668 | |||||||
ER−/HER2+ | OR | 0.763 | 3.019 | 9.125 | 17.116 | ||||||
P | 0.238 | 0.185 | 0.007 | 0.010 | |||||||
95% CI | 0.931-1.018 | 0.588-15.487 | 1.835-45.422 | 1.95-150.355 | |||||||
TNBC | OR | 1.014 | 5.669 | 9.855 | 0.000 | ||||||
P | 0.307 | 0.001 | <0.001 | 0.986 | |||||||
95% CI | 0.987-1.042 | 2.067-15.534 | 3.35-28.991 | 0- >100 | |||||||
Age + Stage + nSES | ER+/HER2+ | OR | 0.998 | 2.497 | 3.655 | 1.904 | 2.440 | 1.723 | |||
P | 0.871 | 0.043 | 0.011 | 0.581 | 0.129 | 0.379 | |||||
95% CI | 0.969-1.027 | 1.027-6.068 | 1.347-9.954 | 0.194-18.728 | 0.771-7.721 | 0.589-2.974 | |||||
ER−/HER2+ | OR | 0.972 | 2.983 | 8.390 | 21.073 | 0.264 | 0.665 | ||||
P | 0.223 | 0.193 | 0.010 | 0.008 | 0.053 | 0.483 | |||||
95% CI | 0.93-1.017 | 0.576-15.456 | 1.667-42.224 | 2.223-199.737 | 0.069-1.016 | 0.213-2.079 | |||||
TNBC | OR | 1.017 | 6.038 | 9.507 | 0.000 | 0.348 | 0.343 | ||||
P | 0.229 | 0.001 | <0.001 | 0.982 | 0.011 | 0.011 | |||||
95% CI | 0.989-1.046 | 1.08-16.81 | 3.177-28.446 | 0- >100 | 0.154-0.789 | 0.151-0.781 | |||||
Age + Stage + Ancestry | ER+/HER2+ | OR | 0.996 | 2.524 | 3.327 | 2.036 | 0.992 | 1.338 | 1.069 | ||
P | 0.080 | 0.041 | 0.020 | 0.540 | 0.873 | 0.382 | 0.228 | ||||
95% CI | 0.967-1.026 | 1.037-6.147 | 1.204-9.198 | 0.21-19.767 | 0.897-1.097 | 0.696-2.57 | 0.959-1.194 | ||||
ER−/HER2+ | OR | 0.969 | 3.736 | 10.299 | 26.076 | 1.100 | 1.533 | 1.120 | |||
P | 0.193 | 0.150 | 0.011 | 0.006 | 0.006 | 0.301 | 0.052 | ||||
95% CI | 0.924-1.016 | 0.621-22.466 | 1.707-62.178 | 2.54-268.003 | 1.027-1.177 | 0.682-3.442 | 0.999-1.256 | ||||
TNBC | OR | 1.015 | 5.795 | 10.054 | 0.000 | 1.062 | 1.057 | 0.997 | |||
P | 0.278 | 0.001 | <0.001 | 0.984 | 0.046 | 0.873 | 0.976 | ||||
95% CI | 0.988-1.043 | 2.071-16.216 | 3.33-30.326 | 0- >100 | 1.001-1.126 | 0.537-2.077 | 0.811-1.225 | ||||
Age + Stage + Ancestry + nSES | ER+/HER2+ | OR | 0.995 | 2.489 | 3.391 | 1.954 | 0.999 | 1.539 | 1.067 | 2.829 | 2.059 |
P | 0.752 | 0.046 | 0.019 | 0.566 | 0.994 | 0.208 | 0.239 | 0.090 | 0.251 | ||
95% CI | 0.966-1.106 | 1.017-6.092 | 1.218-9.44 | 0.199-19.221 | 0.903-1.106 | 0.787-3.007 | 0.958-1.19 | 0.85-9.507 | 0.601-7.05 | ||
ER−/HER2+ | OR | 0.969 | 3.490 | 9.459 | 29.964 | 1.091 | 1.275 | 1.115 | 0.320 | 0.736 | |
P | 0.191 | 0.173 | 0.015 | 0.005 | 0.015 | 0.581 | 0.067 | 0.118 | 0.627 | ||
95% CI | 0.923-1.016 | 0.577-21.115 | 1.56-57.34 | 2.779-323.112 | 1.017-1.169 | 0.537-3.028 | 0.992-1.255 | 0.077-1.332 | 0.215-2.524 | ||
TNBC | OR | 1.018 | 6.135 | 9.905 | 0.000 | 1.049 | 0.896 | 1.006 | 0.366 | 0.366 | |
P | 0.213 | 0.001 | <0.001 | 0.980 | 0.120 | 0.755 | 0.951 | 0.019 | 0.019 | ||
95% CI | 0.99-1.046 | 2.166-17.392 | 3.235-30.356 | 0- >100 | 0.987-1.116 | 0.448-1.793 | 0.82-1.236 | 0.158-0.848 | 0.158-0.850 |
Reference ER+/HER2−
Reference Stage 1
Reference nSES 1: nSES 1: <$35,600, nSES 2: $35,600-55,600, nSES 3: > $55,600