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Effects of ferroptosis on GPX4 in synoviocytes. About 20 μg/L TNF-α and different concentrations of erastin or fer-1 were, respectively, added in cells to co-culture for 48 hr: (a) fluorescent images of cells; (b) GPX4 expression was evaluated by mean fluorescence intensity (#P < 0.05 vs. Ctrl group; ∗P < 0.05 vs. TNF-α group, n = 5).
