Table 1.
Relationship Between circDOCK1 Expression and Clinicopathologic Features in Patients with HER2+ Breast Cancer No. (%)
| Item | Total No. | circDOCK1 | χ 2 | p | |
|---|---|---|---|---|---|
| Low | High | ||||
| Age(years) | 0.048 | 0.84 | |||
| ≤50 | 42 (41.2) | 17 (16.7) | 25 (24.5) | ||
| >50 | 60 (58.8) | 23 (22.5) | 37 (36.1) | ||
| Tumor size | 0.919 | 0.631 | |||
| ≤2cm | 22 (21.6) | 10 (9.8) | 12 (11.8) | ||
| 2–5cm | 55 (53.9) | 22 (21.6) | 33 (32.4) | ||
| >5cm | 25 (24.5) | 8 (7.8) | 17 (16.7) | ||
| Lymph node status | 12.199 | 0.007 | |||
| N0 | 20 (19.6) | 14 (13.7) | 6 (5.9) | ||
| N1 | 32 (31.4) | 13 (12.7) | 19 (18.6) | ||
| N2 | 28 (27.5) | 6 (5.9) | 22 (21.6) | ||
| N3 | 22 (21.6) | 7 (6.9) | 15 (14.7) | ||
| Grade | 3.58 | 0.167 | |||
| I | 30 (29.4) | 16 (15.7) | 14 (13.7) | ||
| II | 41 (40.2) | 14 (13.7) | 27 (26.5) | ||
| III | 31 (30.4) | 10 (9.8) | 21 (20.6) | ||
| ER status | 1.148 | 0.284 | |||
| Positive | 70 (68.6) | 25 (24.5) | 45 (44.1) | ||
| Negative | 32 (31.4) | 15 (14.7) | 17 (16.7) | ||
| PR status | 1.316 | 0.251 | |||
| Positive | 68 (66.7) | 24 (23.5) | 44 (43.1) | ||
| Negative | 34 (33.3) | 16 (15.7) | 18 (17.6) | ||
| Ki67 status | 1.689 | 0.194 | |||
| low | 38 (37.3) | 18 (17.6) | 20 (19.6) | ||
| high | 64 (62.7) | 22 (21.6) | 42 (41.2) | ||
| Relapse | 4.942 | 0.026 | |||
| no | 87 (85.3) | 38 (37.3) | 49 (48.0) | ||
| yes | 15 (14.7) | 2 (2.0) | 13 (12.7) | ||