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. 2024 Nov 19;15:1472194. doi: 10.3389/fpsyt.2024.1472194

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Copyright © 2024 Iqbal, Huang, Shen, Xue, Yang and Jia

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Classification of cellular, biological, and molecular functions based on Gene Ontology (GO) terms regulated by all DEGs. (A–C) Most identified DEGs showed GO enrichment for postsynaptic density protein, glutamatergic synapse, cytosolic ribosome, synapse formation, transmembrane transport protein, actin cytoskeleton reorganization, and protein binding in the PL-control versus PL-susceptible group. (D–F) In comparison to the IL-control group, the IL-susceptible group demonstrated enrichment of GO terms involved in synapse formation, neuronal activity, dendrite formation, axon regeneration, learning processes, and glucocorticoid receptor binding. (n=4 in each group) (FDR corrected q-value ≤ 0.05).