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. 2024 Dec 2;14:29990. doi: 10.1038/s41598-024-81795-z

Table 4.

Treatment outcomes based on different body mass index before and after Botulinum toxin injection therapy.

Normal weight
18.5 ≦ BMI<24 (n = 17 )
Overweight 24 ≦ BMI<27 (n = 15) Obese
27 ≦ BMI (n = 13)
p
UDI-6
 Pre-treatment 9.0 ± 3.7 8.4 ± 4.1 7.4 ± 3.1 0.519
 Post-treatment 3.9 ± 3.8 5.4 ± 3.6 3.4 ± 1.5 0.182
 Difference − 4.3 ± 4.0 − 4.7 ± 4.6 − 3.8 ± 3.5 0.689
 P (intergroup) 0.020 0.035 0.045
IIQ-7
 Pre-treatment 12.1 ± 6.0 10.3 ± 6.7 11.7 ± 7.4 0.771
 Post-treatment 5.4 ± 8.2 5.4 ± 5.7 5.5 ± 7.3 0.759
 Difference − 5.5 ± 7.9 − 8.0 ± 8.7 − 5.3 ± 7.8 0.808
 P (intergroup) 0.050 0.035 0.142
OABSS
 Pre-treatment 9.2 ± 2.9 10.1 ± 2.8 10.3 ± 3.7 0.121
 Post-treatment 5.0 ± 4.0 6.1 ± 4.8 5.8 ± 3.7 0.540
 Difference − 3.9 ± 5.9 − 4.3 ± 4.8 − 4.4 ± 4.6 0.991
 P (intergroup) 0.016 0.033 0.015
Micturition episodes
 Pre-treatment 10.8 ± 5.0 8.6 ± 3.8 9.7 ± 4.1 0.400
 Post-treatment 5.7 ± 3.7 7.3 ± 4.8 4.6 ± 1.7 0.350
 Difference − 4.6 ± 5.3 − 2.9 ± 6.4 − 6.8 ± 5.0 0.501
 P (intergroup) 0.023 0.281 0.039
Nocturia episodes
 Pre-treatment 2.8 ± 2.1 3.4 ± 1.6 3.1 ± 1.9 0.746
 Post-treatment 1.6 ± 1.4 2.4 ± 1.6 1.5 ± 1.6 0.378
 Difference − 1.2 ± 1.1 − 1.6 ± 1.3 − 1.8 ± 2.0 0.264
 P (intergroup) 0.036 0.017 0.079
Urgency episodes
 Pre-treatment 6.0 ± 4.6 5.5 ± 3.8 7.9 ± 6.2 0.455
 Post-treatment 2.4 ± 3.5 2.5 ± 3.1 1.8 ± 2.2 0.657
 Difference − 4.0 ± 5.2 − 5.1 ± 5.7 − 7.8 ± 6.0 0.301
 P (intergroup) 0.044 0.047 0.043
Urinary incontinence episodes
 Pre-treatment 3.4 ± 4.7 2.3 ± 1.9 2.2 ± 1.5 0.418
 Post-treatment 0.6 ± 0.8 1.1 ± 1.3 0.8 ± 1.2 0.778
 Difference − 2.7 ± 13.0 − 2.0 ± 1.9 − 1.2 ± 2.4 0.810
 P (intergroup) 0.038 0.027 0.324

Data are presented as mean ± standard deviation or as number (percent) of patients.

UDI-6: the short form of the Urogenital Distress Inventory, IIQ-7: the short form of the Incontinence Impact Questionnaire, OABSS: overactive bladder symptom score.