Table 1.
Genes containing variants associated with IFNγ levels in clinical isolates
| Category | Chromosome | Gene | SNP location | Gene function |
|---|---|---|---|---|
| Fatty acid synthesis | 6 | PHS1 (CNAG_02487) | Upstream of coding region | 3-hydroxy acyl-CoA dehydratase involved in synthesis of branched chain fatty acids |
| 9 | CNAG_04101 | Coding region; non-synonymous | Hypothetical; orthologous to phytanoyl-CoA hydroxylase | |
| Amino acid metabolism | 14 | CNAG_05664 | Upstream of coding region | Branched-chain-amino-acid transaminase |
| Inositol sensing and metabolism | 14 | ITR4 (CNAG_05662) | Downstream of coding region | Membrane bound inositol signaler |
| 4 | CNAG_05329 | Upstream of coding region | myo-inositol 2-dehydrogenase | |
| Enzyme regulator | 5 | CNAG_01241 | Upstream of coding region | Enzyme regulator; putative role in protein signal transduction |
| DNA structure | 1 | CNAG_07950 | Upstream of coding region | Hypothetical protein; centromeric |
| 3 | CNAG_07528 | Coding region; non-synonymous | DNA binding protein; potential transposon | |
| 13 | CNAG_06256 | Upstream of coding region | Hypothetical protein; subtelomeric |