Table 1.

The summary Papp and ER calculated from transport study using gut MPS Data are presented as the mean ± SD (inhibitor (-): n = 4, inhibitor (+): n = 3).

	Antipyrine	Atenolol	Midazolam	Quinidine	Sulfasalazine
Papp, basal to apical, inhibitor (-) (10−6 cm/s)	13.2 ± 1.1	not determined	not determined	4.37 ± 0.15	6.44 ± 0.45
Papp, apical to basal, inhibitor (-) (10−6 cm/s)	20.1 ± 2.7	1.31 ± 0.19	11.2 ± 0.6	2.15 ± 0.33	0.505 ± 0.072
Papp, basal to apical, inhibitor (+) (10−6 cm/s)	14.4 ± 0.7	not determined	not determined	4.37 ± 1.53	1.10 ± 0.29
Papp, apical to basal, inhibitor (+) (10−6 cm/s)	18.5 ± 1.2	0.865 ± 0.173	14.4 ± 1.9	3.88 ± 1.12	0.557 ± 0.095
Efflux ratio (ER), inhibitor (-)	0.656 ± 0.120	-	-	2.02 ± 0.37	12.7 ± 2.3
Efflux ratio (ER), inhibitor (+)	0.780 ± 0.076	-	-	1.12 ± 0.63	1.97 ± 0.76