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. 2024 Dec 3;14:30012. doi: 10.1038/s41598-024-81433-8

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© The Author(s) 2024, corrected publication 2025

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Fig. 6 — AF variance across the 3 age groups. Each age group shows the high contrast average image of the RPE cells on the left and the AF variance heatmap on the right. (a) shows the RPE from a 20 y.o. female at the fovea. The cyan box represents a group of cells that show relatively high AF variance within the image whereas the red box shows a group of cells with relatively low AF variance. A zoomed-in-view of those cells can be seen within the rectangle with its corresponding color. (b) Shows the RPE from a 53 y.o. male at temporal and (c) shows the RPE from a 64 y.o. female also at temporal. The scale bars represent 50 m.

Inline graphic — AF variance across the 3 age groups. Each age group shows the high contrast average image of the RPE cells on the left and the AF variance heatmap on the right. (a) shows the RPE from a 20 y.o. female at the fovea. The cyan box represents a group of cells that show relatively high AF variance within the image whereas the red box shows a group of cells with relatively low AF variance. A zoomed-in-view of those cells can be seen within the rectangle with its corresponding color. (b) Shows the RPE from a 53 y.o. male at temporal and (c) shows the RPE from a 64 y.o. female also at temporal. The scale bars represent 50 m.