Table 2.
Mean dosimetric values per fraction concerning target coverage and OAR dose for both the scheduled and adapted treatment plans including all 10 patients
| Dose/volume parameter | Scheduled mean ± SD | Adapted mean ± SD | Absolute difference mean ± SD | Relative difference (%) | P value | |
|---|---|---|---|---|---|---|
| PTV | D99% (%) | 79.7 ± 8.6 | 94.1 ± 3.9 | 14.4 ± 2.6 | +15.3 | <.001 |
| D95% (%) | 92.3 ± 3.9 | 97.3 ± 1.9 | 5.0 ± 1.2 | +5.1 | .003 | |
| D1% (%) | 103.8 ± 1.6 | 102.1 ± 0.3 | –1.7 ± 0.5 | –1.7 | .005 | |
| CTV | D99% (%) | 93.3 ± 4.5 | 98.2 ± 0.3 | 4.9 ± 1.4 | +5.0 | .008 |
| D95% (%) | 97.8 ± 1.7 | 98.9 ± 0.2 | 1.1 ± 0.5 | +1.1 | .070 | |
| D1% (%) | 103.9 ± 1.4 | 101.7 ± 0.4 | –2.2 ± 0.4 | –2.2 | <.001 | |
| Heart | Dmean (Gy) | 18.5 ± 3.9 | 16.9 ± 3.6 | –1.6 ± 0.4 | –9.5 | .006 |
| Lungs | V20Gy (%) | 15.9 ± 4.9 | 13.6 ± 4.8 | –2.3 ± 0.3 | –16.9 | <.001 |
Target dose parameters are reported in percent values, whereas 1.8 Gy (prescribed fraction dose) equals 100%.
Abbreviations: CTV = clinical target volume; Dmean = mean dose; OAR = organ at risk; PTV = planning target volume.