TABLE 5.

Genes modulated similarly by HCMV and UV-HCMV

Gene	Nuc IDa	HCMV fold changeb	UV-HCMV fold changeb
2′-5′oligoadenylate synthetase-like	AJ225089	57.1, 26.1	74.7, 65.1
Activating transcription factor 3 (ATF3)	L19871	6.5, 8.6	47.3, 47.9
Acute myeloid leukemia protein	X90976	−3.4, −4.1	−3.7, −3.8
ADP-ribosylation factor-like 7	AB016811	∼−19.0, ∼−16.2	−3.3, −3.5
Adrenomedullin	D14874	−11.8, −11.5	−11, −12.1
AML1 mRNA for AML1b protein (alternatively spliced product)	D43968	−6.1, −11.5	−3.7, −3.9
Apolipoprotein AI regulatory protein (ARP-1)	M64497	−5.1, −5.6	−5.5, −5.5
B2-bradykinin receptor 3	X86163	−8.2, −7.9	−7.7, −9.1
beta-transducin repeat containing protein	Y14153	∼5.0, ∼8.9	∼5.4, ∼4.6
C2f	U72514	∼−6.9, −3.7	−6.3, ∼−12.6
cAMP-responsive element modulator	S68271	3.8, 4.3	5.3, 4.7
cdc25 homolog	S78187	−3.1, −2.3	−8.3, −4.6
Cdc42 effector protein 2	AF001436	−3.7, ∼−11.3	∼−11.4, ∼−8.8
c-fos	V01512	11.1, 8.5	23, 23.7
Chromosome 12 open reading frame	AF052105	4.1, 4.5	4.4, 4.4
Cleavage stimulation factor, 3′ pre-RNA, subunit 1, 50 kDa	L02547	∼6.1, −5.4	∼−12.7, −7.9
Core-binding factor, runt domain, alpha subunit 2; cyclin D-related	D43638	−6, −6.9	−3.2, −4
Cyclin E2	AF091433	4.6, ∼6.6	∼4.7, ∼6.6
Cyclin-dependent kinase inhibitor 1B (p27, Kip1)	AI304854	∼−16.0, −10.8	−5.6, −8.4
Cyclooxygenase 2	U04636	5.7, 3.9	25.6, 23.3
DKFZP564B0769 protein	AL080186	∼−8.9, ∼−5.7	∼−9.0, ∼−6.4
DKFZP586K1520 protein	AL050153	−4.1, −4.5	∼−12.4, ∼−13.5
DNA sequence from clone 1175I6 on chromosome 20	AL049538	−3.2, −3	−3.1, −3.2
Dual-specificity phosphatase 10	AB026436	∼−8.9, ∼−11.9	∼−12.6, −3.9
EGR alpha	S81439	−6.5, −3.6	−3.8, −4.5
ESTs	H94842	−9, −4.6	−5.5, −7.2
Fucose-1-phosphate guanylyltransferase	AF017445	−3.8, −7.5	−3.4, −3.1
Gamma-interferon-inducible early response gene (homology to platelet proteins)	X02530	∼3.0, ∼7.4	∼199.1, ∼179.1
gas1	L13698	−27.1, −37.7	−24, −19.4
Growth differentiation factor 5 (cartilage-derived morphogenetic protein 1)	X80915	∼−24.0, ∼−24.0	∼−19.6, ∼−25.3
GS3955	D87119	∼−19.9, ∼−20.0	−9.9, −12.6
GTP cyclohydrolase 1 (dopa-responsive dystonia)	U19523	3.6, ∼7.2	∼34.9, ∼29.2
homeo box A9	U41813	∼−8.9, ∼−9.2	∼−10.9, ∼−11.9
Homo sapiens cDNA FLJ13555 fis, clone PLACE1007677	AL080210	∼−7.5, ∼−5.4	∼−6.7, ∼−7.0
Homo sapiens cDNA, 5′ end	N36638	−7.3, −8.9	−6.4, −7.1
Homo sapiens cig5 mRNA,  partial sequence	AF026941	∼12.7, ∼18.9	∼326.2, ∼290.8
Homo sapiens mRNA; cDNA DKFZp564G103	AL049268	∼−5.7, ∼−5.0	∼−6.1, ∼−6.5
hSIAH1	U76247	−3, −4.1	−3.4, −3.7
hTCF-4	Y11306	∼−22.5, ∼−13.2	∼−18.3, ∼−17.2
Hypothetical protein	AA522530	−4.1, −3.6	−9.8, −3.7
Hypothetical protein LOC57187	AA928996	∼−9.5, ∼−6.5	∼−4.2, ∼−5.1
Hypothetical protein FLB6421	AI133727	6, 5.4	9.4, 9
Hypothetical protein FLJ10262	AA115140	−5.2, −6.3	−5.7, −5
Inhibitor of DNA binding 2, dominant-negative helix-loop-helix protein	D13891	−3.9, −3	−10.2, −6.6
Interferon-induced protein with tetratricopeptide repeats 4	AF026939	11.3, 8.8	8.6, 7.4
Interleukin 11	X58377	∼41.1, ∼53.5	∼133.9, ∼113.1
ISG-54K gene (interferon-stimulated gene)	M14660	32.2, 16.7	11, 10.6
KIAA0112 protein; homolog of yeast ribosome biogenesis regulatory protein RRS1	D25218	∼−8.3, −5.3	∼−12.7, ∼−11.4
KIAA0671 gene product	AB014571	−10.1, −8.9	−10.8, −9.6
KIAA1010 protein	AB023227	−3.4, −6.5	−11.1, −7.9
KIAA1116 protein	AB029039	−3.9, −3.3	−4.4, −4.6
KIAA1288 protein	AL096842	∼−5.9, ∼−3.2	∼−7.2, ∼−4.5
Monoclonal antibody 21 (Caenorhabditis elegans)-like 1	U38810	−13.9, −30.5	−14.7, −9.7
Meis1 (mouse) homolog	U85707	−5.5, ∼−21.8	−6.5, −5
Mitogen-induced nuclear orphan receptor (MINOR)	U12767	8, 13.3	7.5, 5.7
MN1	X82209	−21, ∼−34.0	∼−31.6, ∼−31.4
Myxovirus resistance 1, homolog of murine (interferon-inducible protein p78)	M33882	5.2, 3.9	20.2, 17.4
Novel human gene mapping to chomosome 13, similar to rat RhoGAP	AL049801	−3.5, ∼−15.9	−4.9, −4
Nuclear factor of activated T cells, cytoplasmic, calcineurin-dependent 4	L41066	∼−18.6, ∼−14.3	∼−8.2, ∼−10.7
Nuclear receptor subfamily 4, group A, member 2	X75918	∼8.4, ∼9.9	∼9.5, ∼10.5
Nuclear receptor subfamily 4, group A, member 3	U12767	∼23.3, ∼41.5	∼29.8, ∼19.0
Phorbol-12-myristate-13-acetate-induced protein 1	D90070	9.3, 10.8	30.7, 25.7
Phosphodiesterase 4B	L20971	−11.2, −18.8	−3.4, −4.4
Pleckstrin homology, Sec7 and coiled/coil domains 1 (cytohesin 1)	M85169	7.7, 4.2	7.2, 6.7
Polymerase (DNA directed), gamma 2, accessory subunit	U94703	4.6, ∼24.3	∼7.6, ∼6.6
Protein phosphatase 1 (PPP1R5)	Y18207	−7.6, −6.2	−6.1, −5.3
RAN-binding protein 6	AF039023	∼−3.8, −3.4	−3.2, −3.9
ras homolog gene family, member E	S82240	−5.9, −5.8	−3.4, −3.6
ras inhibitor	L36463	−3.5, −5.4	−3.2, −3.6
RIP protein kinase	U50062	3, 3	8.5, 7.3
runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)	D43969	∼−39.3, ∼−42.2	∼−41.6, ∼−43.1
slug (chicken homolog), zinc finger protein	U69196	−11, ∼−19.5	−13.6, −9.2
Solute carrier family 7	M80244	4.5, 3.7	4, 4.3
Stromal cell-derived factor 1	L36033	−4.2, −4.5	−6.3, −9.7
Thyroid receptor interactor (TRIP14)	L40387	4.1, 7.4	61.8, 53.8
TR3 orphan receptor	L13740	6.3, 13.7	33.9, 26.9
Transcription factor 21	AF047419	−3.9, ∼−23.0	−3.2, −4
v-myc avian myelocytomatosis viral oncogene homolog	V00568	∼−12.9, ∼−9.8	∼−12.9, −6.4
wee1+ (S. pombe) homolog	X62048	−5.3, −5.3	−4.3, −3.5
zinc finger protein 183 (RING finger, C3HC4 type)	X98253	∼−3.8, ∼−5.8	∼−7.9, ∼−7.5
zinc finger protein 217	AF041259	∼−27.9, ∼−41.2	−8, −6.6

^aNuc ID, nucleotide sequence identification or sequence accession number. 

^bTwo fold change values were determined in independent experiments. A ∼ symbol in front of a fold change value indicates that the transcript was scored as absent in either the baseline on experimental sample and that the fold change was then calculated using the background noise value as the intensity for that comparison. The complete data set with difference calls can be accessed at http://www.molbio.princeton.edu/labs/shenk/browneetal2001/.