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. 2024 Dec 2;7(12):e2448405. doi: 10.1001/jamanetworkopen.2024.48405

Table 3. Augmenting MOUD With Smartphone App–Based CM Treatment Outcomes.

Outcome β (95% CI) P value
Days of opioid use at end of treatment a
Treatment setting 1.56 (−2.81 to 5.93) .48
MOUD
Buprenorphine to naltrexone 5.53 (−8.29 to 19.35) .43
Buprenorphine to methadone 9.15 (−0.29 to 18.59) .06
Methadone only 0.60 (−3.80 to 5.00) .79
Treatment group −6.10 (−8.09 to −4.10) <.001
Retention b
Treatment setting 38.95 (−0.58 to 78.48) .053
MOUD
Buprenorphine to naltrexone −154.72 (−250.23 to −59.20) .01
Buprenorphine to methadone −67.11 (−140.02 to 5.80) .07
Methadone only 35.58 (−4.32 to 75.48) .08
Treatment group 51.91 (33.86 to 69.95) <.001

Abbreviations: CM, contingency management; MOUD, medication for opioid use disorder.

a

Linear regression analysis.

b

Cox proportional hazards regression analysis. Reference groups: office-based opioid treatment (treatment setting), buprenorphine only (MOUD), and MOUD only (treatment group).