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. 1980 Jan 1;185(1):265–268. doi: 10.1042/bj1850265

Properties of the non-specific calcium-binding sites of rabbit skeletal-muscle myosin.

J Wikman-Coffelt
PMCID: PMC1161294  PMID: 6769430

Abstract

The non-specific Ca2+-binding sites of skeletal-muscle myosin are located on the light chains; with the dissociation of light chains there is a corresponding decrease in the number of Ca2+-binding sites on light-chain-deficient myosin. The released light chains have a decreased binding affinity. Myosin heavy chains indirectly influence the Ca2+-binding properties of light chains by increasing the affinity of light chains for bivalent cations; this influence varies with pH. Because of light-chain dissociation at low Ca2+ and/or Mg2+ concentrations, anomalies may exist when analyses of non-specific Ca2+-binding properties of myosin are assessed by dialysis equilibrium.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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