Table 2.
Mechanisms of small nucleolar RNAs (snoRNA) host genes (SNHGs) in cancer.
| SNHG | snoRNA | Mechanism | Biological function | Tumor type | Refs. |
|---|---|---|---|---|---|
| SNHG5 | U50 | Trapping MTA2 in the cytosol | Inhibiting tumor development | Gastric cancer | [94] |
| SNHG6 | / | Sponging miR-26a | Promoting tumorigenesis and metastasis | CRC | [95] |
| SNHG15 | / | Sponging miR-338-3p | Promoting proliferation | Prostate cancer | [96] |
| SNHG12 | / | Sponging miR-16-5p | Promoting growth and invasion | Papillary thyroid cancer | [97] |
| SNHG17 | SNORA71B | Sponging miR-339-5p | Promoting tumorigenesis and metastasis | Prostate cancer | [100] |
| SNHG10 | SCARNA13 | Sponging miR-150-5p | Promoting tumorigenesis and metastasis | Hepatocellular cancer | [101] |
| SNHG5 | SNORA50C | Recruiting DKC1 | Promoting tumorigenesis and metastasis | Hepatocellular cancer | [102] |
/: no data. MTA2: metastasis-associated protein 2; CRC: colorectral cancer; DKC1: dyskerin pseudouridine synthase 1.