Table-I.
Patient characteristics | Total (n=100) | Bacteremia (n=19) | Non-bacteremia (n=81) | P-value |
---|---|---|---|---|
Age | ||||
Less than 40 years | 45 | 9 | 36 | 0.818 |
Greater than 40 years | 55 | 10 | 45 | |
Gender | ||||
Female | 57 | 8 | 35 | 0.930 |
Male | 43 | 11 | 46 | |
Disease classification | ||||
SJS | 70 | 10 | 60 | |
TEN | 18 | 4 | 14 | 0.077 |
SJS and TEN overlap | 12 | 5 | 7 | |
Past medical history | ||||
Hypertension | 39 | 7 | 32 | 0.830 |
Diabetes | 22 | 5 | 17 | 0.614 |
Neuro-psychiatric illness | 17 | 4 | 13 | 0.601 |
Chronic Kidney Disease | 10 | 4 | 6 | 0.074 |
Ischemic Heart Disease | 9 | 4 | 5 | 0.041 |
Malignancy | 4 | 2 | 2 | 0.162 |
Respiratory Disease | 3 | 2 | 1 | 0.033 |
Autoimmune diseases | 2 | 0 | 2 | 0.489 |
Endocrine diseases | 1 | 0 | 1 | 0.626 |
Chronic liver diseases | 1 | 0 | 1 | 0.626 |
Prior history of SJS | 3 | 0 | 3 | 0.528 |
Clinical manifestation | ||||
No sepsis | 8 | 0 | 8 | |
Sepsis | 73 | 9 | 64 | <0.001 |
Septic Shock | 19 | 10 | 9 | |
Positive history of precipitating drug use | 67 | 14 | 53 | 0.378 |
SCORTEN score | 0.040 | |||
Less than 4 | 76 | 11 | 65 | |
Equal to or more than 4 | 24 | 8 | 16 | |
ICU admission | 12 | 7 | 5 | <0.001 |
Complications | ||||
Electrolyte imbalance | 56 | 17 | 39 | 0.001 |
Acute kidney injury | 43 | 11 | 32 | 0.145 |
Liver injury | 40 | 12 | 28 | 0.026 |
Deranged coagulation | 20 | 11 | 9 | <0.001 |
Elevated troponin | 13 | 6 | 7 | 0.007 |
Infective parameters [Median (IQR)] | ||||
C-reactive protein (ug/mL) | 12.7 (4.2-17.4) | 13.7 (4.6-19.0) | 12.0 (3.9-16.9) | 0.411 |
Procalcitonin (ng/mL) | 1.1 (0.2-6.4) | 9.7 (0.9-35.7) | 0.4 (0.1-2.8) | 0.007 |
Length of stay | ||||
Less than 7 days | 67 | 12 | 55 | |
Equal or more than 7 days | 33 | 7 | 26 | 0.692 |
Outcome | ||||
Discharged | 81 | 9 | 72 | |
Expired | 15 | 9 | 6 | <0.001 |
LAMA | 4 | 1 | 3 |