Table 1.

Difference in care received in the PROMISE-EPI intervention and control arms, Lusaka, Zambia

Intervention arm	Control arm
PROMISE-EPI prevention package	Zambian standard of care
- POC for maternal viral load monitoring at EPI-2 and M6 - Immediate single-drug (lamivudine) infant prophylaxis initiation in case of mother viral load ≥ 1000cp/ml - Monthly visits for infants on lamivudine	Before 2020: - Viral load monitoring every 6 months during the breastfeeding period	After 2020: - Extended three drug infant prophylaxis (AZT/3TC + NVP) in case of maternal viral load ≥ 1000 cp/ml at 10 weeks and maternal viral load follow-up every 3 months

POC point-of-care, EPI-2 second visit of the expanded program on immunization, AZT zidovudine, 3TC lamivudine, NVP nevirapine